| Acronym | Sense | Language | Topics |
|---|---|---|---|
| ISS | Institute for Strategic Studies | In English | → International relations |
| ISS | International Space Station | In English | → Astronautics |
| ISS | Inertial Subsystem | In English | |
| ISS | Information Subsystem | In English | |
| ISS | Installation Support Services | In English | |
| ISS | Instruction Summary Sheet | In English | |
| ISS | Integrated Scheduling System | In English | |
| ISS | Integrated System Schematic | In English | |
| ISS | Industrielle Sensorsysteme | In German | → Electronics |
| ISS | Institute of Social Studies | In English | → Organizations and associations → Sociology |
| ISS | Incident Significatif de Sûreté | In French | → Accidents, risks, safety |