

| Acronym | Sense | Language | Topics | 
|---|---|---|---|
| IPTM | Institute of Police Technology and Management | In English | → Specialized or polytechnical colleges → Police | 
| IPTR | In-Process Technical Review | In English | → Engineering, technology | 
| IPTS | Indicateur de Prix des Travaux Souterrains | In French | → Prices → Civil engineering | 
| IPU | Inter-Parliamentary Union | In English | → International relations → Parliaments, representation | 
| IPWG | Integrated Project Working Group | In English | |
| IQ | Ingénieur Qualité | In French | → Quality management | 
| IQ | Intellectual Quotient | In English | → Neurology | 
| IQOQI | Institut für Quantenoptik und Quantenkommunikation (www.iqoqi.at) = IQOQI | Institute for Quantum Optics and Quantum Information | In English | In German | → Research institutes → Optics → Quantum mechanics → Austria | 
| IQOQI | Institute for Quantum Optics and Quantum Information (www.iqoqi.at) = (look above) | In English | → Research institutes → Optics → Quantum mechanics → Austria | 
| IQSA | International Qajar Studies Association | In English | → Associations | 
| IQSY | International Quiet Sun Year | In English | → Astronomy | 
| IQT | Initial Qualification Training | In English | → Education | 
| IR | Investor Relations | In English | → Finance | 
| IR | Infrared | In English | → Physics | 
| IR | Inner Roll | In English | |
| IR | Inside Radius | In English | |
| IR | Interchangeability and Replaceability | In English | → Engineering, technology | 
| IR | Interrogator-Responder | In English | |
| IR | Information Retrieval | In English | → Libraries | 
| İR | İsay ra Raver | In Dimli (Zazaki) | |
| IR&D | Independent Research and Development | In English | → Research policy → Engineering, technology | 
| IRA | Individual Retirement Account | In English | → Labour, labour economics → Finance | 
| IRA | Infrared Astronomy | In English | → Serial publications, periodicals → Astronomy | 
| IRA | Institut Régional d'Administration | In French | → Specialized or polytechnical colleges → Public administration, government | 
| IRA | Insuffisance Rénale Aiguë | In French | → Pathology | 
| IRA | Indemnité de Responsabilité Administrative | In French | → Personnel management → Public administration, government | 
| IRA | Infection Respiratoire Aiguë | In French | → Chest diseases | 
| IRAB | Infection Respiratoires Aiguë Basse | In French | → Infectious diseases | 
| IrAJ | Irish Astronomical Journal | In English | → Serial publications, periodicals → Astronomy | 
| IrAJS | Irish Astronomical Journal Supplement | In English | → Serial publications, periodicals → Astronomy | 
| IRAL | International Review of Applied Linguistics (www.degruyter.de/journals/iral/) | In English | → Serial publications, periodicals → Linguistics | 
| IRAM | Instituto Argentino de Racionalización de Materiales (www.iram.com.ar) | In Spanish | → Standardization → Argentina | 
| IRAM | Input Random Access Memory | In English | → Memories | 
| IRAM | Institut de Radioastronomie Millimétrique | In French | → Research institutes → Astronomy | 
| IRAMS | Inertial Reference Alignment Monitor System | In English | |
| IRAN | Iranian Resources for Academic Needs | In English | → Libraries | 
| IRANDOC | Iranian Information & Documentation Center | In English | → Documentation | 
| IRANET | Iranian Research and Academic Network | In English | → Research policy → Education | 
| IRANSAT | Iranian government communications satellite | In English | → Astronautics → Telecommunications | 
| IRAS | Inland Revenue Authority of Singapore | In English | → Public administration, government | 
| IRAS | Infrared Astronomical Satellite | In English | → Astronomy → Astronautics | 
| IRAS | Internet Review Arno Schmidt | In English | → Serial publications, periodicals → Internet | 
| IRAS | Interreligiöse Arbeitsgemeinschaft in der Schweiz | In German | → Associations → Religion, theology → Switzerland | 
| IRAS | Istituto Spezzino Ricerche Astronomiche | In Italian | → Research institutes → Astronomy | 
| IRASEC | Institut de Recherche sur l'Asie du Sud-Est Contemporaine | In French | → Area studies | 
| IRB | Internal Ratings-Based | In English | |
| IRB | Institutional Review Board | In English | → Ethics → Medicine | 
| IRB | International Rugby Board | In English | → Organizations and associations → Football and rugby | 
| IRBD | International River Basin District | In English | → 341224 → 626 → 627 | 
| IRBM | Intermediate-Range Ballistic Missile | In English | → Military engineering | 
| IRBM | Intermediate Range Ballistic Missile | In English | → Military engineering | 
| IRBS | Infrared Background Sensor | In English | → Astronomy | 
| IRBS | Intermediate-Range Ballistic System | In English | → Military engineering | 
| IRBS | Intermediate-Range Booster System | In English | → Astronautics | 
| IRC | Innovation Relay Centre | In English | → Engineering, technology | 
| IRC | Internet Relay Chat | In English | → Software → Internet | 
| IRC | Insufisance Rénale Chronique | In French | → Pathology | 
| IRCA | Innovation Relay Centre Austria (www.irca.at) | In English | → Mathematics and natural sciences → Applied sciences, technology → Austria | 
| IRCAD | Institut de Recherche contre les Cancers de l'Appareil Digestif (https://www.ircad.fr/) | In French | → Research institutes → Oncology → France | 
| IRCAM | Institut de Recherche et Coordination Acoustique/Musique (www.ircam.fr) | In French | → Research institutes → Music → Acoustical engineering → France | 
| IRCANTEC | Institution de Retraite Complémentaire des Agents Non Titulaires de l'État et des Collectivités locales | In French | → Insurance → Labour, labour economics → France | 
| IRCC | Institute for Research on Contemporary China | In English | → Research institutes → Area studies → China | 
| IRCCS | Istituto di Ricovero e Cura a Carattere Scientifico | In Italian | → Research institutes → Research policy | 
| IRCCyN | Institut de Recherche en Communications et Cybernétique de Nantes (www.irccyn.ec-nantes.fr) | In French | → Research institutes → Telecommunications → Electronics → France | 
| IRCFE | Infrared Communications Flight Experiment | In English | → Astronautics → Telecommunications | 
| IRCGN | Institut de Recherche Criminelle de la Gendarmerie Nationale | In French | → Criminology | 
| IRCICA | Research Centre for Islamic History, Art and Culture | In English | → Research institutes → Islam → Arts → History → Civilization, culture, progress | 
| IRCJS | International Research Center for Japanese Studies | In English | → Research institutes → Area studies | 
| IRCL | International Review of Chinese Linguistics | In English | → Serial publications, periodicals → Linguistics → China | 
| IRCOBI | International Research COmmittee on Biokinetics of Impact | In French | → Transport and postal services | 
| IRCOM | Institut des relations publiques et de la communication | In French | → Higher education, universities → 659 | 
| IRCS | Integrated Resource Control System | In English | |
| IRCT | International Rehabilitation Council for Torture Victims | In English | |
| IRD | Institut de Recherche pour le Développement | In French | → Development | 
| IRD | Inland Revenue Department | In English | → Economics → Central administration | 
| IRD | Information Requirements Description | In English | → Knowledge management | 
| IRD | Information Requirements Document | In English | → Knowledge management | 
| IRD | Initiating Reference Document | In English | |
| IRD | Integration Requirements Document | In English | |
| IRD | Interface Requirements Document | In English | → Human-computer interaction | 
| IrDA | Infrared Data Association | In English | → Associations → Telecommunications | 
| IRDS | Information Resource Dictionary System | In English | |
| IRE | INstitute of Radio Engineers | In English | → Telecommunications | 
| IRE | Institutul Naţional Român pentru Studiul Amenajării şi Folosirii Surselor de Energie | In Romanian | → Organizations and associations → Energy economics | 
| IREA | Irana Esperanto-Asocio | In Esperanto | → Associations → Artificial languages (linguistics) | 
| IREJO | Irana Esperantista Junulara Organizo | In Esperanto | → Organizations and associations → Artificial languages (linguistics) | 
| IREM | Institut de Recherches sur l'Enseignement des Mathématiques | In French | → Research institutes → Education → Mathematics | 
| IREP | Institut de Recherches et d'Études Publicitaires | In French | → Advertising | 
| IRES | Istituto di Ricerche Economiche e Sociali | In Italian | → Economics → Social welfare | 
| IRES | Institut de Recherches Économiques et Sociales | In French | → Research institutes → Social sciences → Economics | 
| IRESCO | Institut de Recherche Européen en Sociologie et Socio-économie | In French | → Research institutes → Sociology → Economics | 
| IRESCO | Institut de Recherche sur les Sociétés Contemporaines | In French | → Research institutes → Sociology | 
| IRESP | Institut de Recherche en Santé Publique | In French | → Pharmacology, toxicology | 
| IREWG | Institute for Research and Education on Women and Gender (www.womenandgender.buffalo.edu) | In English | → Research institutes → Education → Social sciences → Feminism | 
| IREX | Institut pour la Recherche appliquée et l'EXpérimentation en génie civil | In French | → Civil engineering | 
| IRF | Interreligiöses Forum Basel | In German | → Religion, theology | 
| IRG | Inertial Rate Gyro | In English | |
| IRG | (Marie Curie) International Reintegration Grants | In English | → Research policy → Labour, labour economics | 
| IRG | Internationale des Résistants à la Guerre | In French | → Anarchist organizations | 
| IRH | International Review of Hydrobiology | In English | → Serial publications, periodicals → Biological sciences | 
| IRH | Institut des Ressources Humaines (www.irh-sup.com) | In French | → Specialized or polytechnical colleges → Personnel management | 
| IRI | Islamic Research Institute | In English | → Research institutes → Islam | 
| IRI | Internationalized Resource Identifier | In English | → Networks, communication | 
| IRI | Institut de Recherche et d'Innovation (www.iri.centrepompidou.fr) | In French | → Research institutes → Research policy → Civilization, culture, progress → France | 
| IRIG | Inertial Rate Integrating Gyroscope | In English | |
| IRIG | Inertial Reference Integrating Gyroscope | In English | |
| IRIG | Interrange Instrumentation Group | In English | → Engineering, technology | 
| IRIS | Institut des Relations Internationales et Stratégiques (www.iris-france.org) | In English | → Research institutes → International relations | 
| IRIS | Imaginons un Réseau Internet Solidaire | In French | → Internet → Organizations and associations | 
| IRIS | Infrared Instrumentation System | In English | |
| IRIS | Italian Research Interim Stage | In English | → Research policy → Italia | 
| IRIS | Indexation et Reconnaissance d'Images par la Sémantique | In French | → Image processing → Semiotics | 
| IRIS | Inter-Regiona Internacia Semajno | In Esperanto | → Congresses | 
| IRIS | Incorporated Research Institutions for Seismology (www.iris.edu) | In English | → Research institutes → Seismology, earthquakes | 
| IRIS | Immobilisations Regroupées et Inventoriées sous SAP | In French | → Software → Accounting | 
| IRIS | Institut de Recherches sur les Implications de la langue des Signes | In French | → Research institutes → Linguistics | 
| IRIT | Institut de Recherche Informatique de Toulouse (www.irit.fr) | In French | → Research institutes → Computer science → France | 
| IRIT | Institut de Recherche en Informatique de Toulouse | In French | → Research institutes → Computer science | 
| IRIZ | International Research Institute for Zen Buddhism (http://iriz.hanazono.ac.jp) | In English | → Research institutes → Buddhism → Japan | 
| IrJST | Iranian Journal of Science and Technology | In English | → Serial publications, periodicals → Mathematics and natural sciences → Engineering, technology | 
| IRK | Internacia Respondkupono | In Esperanto | → Artificial languages (linguistics) | 
| IRKS | Institut für Rechts- und Kriminalsoziologie | In German | → Sociology → Law, jurisprudence | 
| IRL | Initiating Reference List | In English | |
| IRL | Interface Requirements List | In English | → Human-computer interaction | 
| IRM | Imagerie par Résonance Magnétique = MRI | Magnetic Resonance Imagery | In English | In French | → Medicine → Nuclear, atomic, and molecular physics | 
| IRM | Information Resource Management | In English | → Knowledge management | 
| IRM | Integrated Range Mission | In English | |
| IRM | Institut Royal Météorologique de Belgique = KMI | Koninklijk Meteorologisch Instituut | In Dutch | In French | → Meteorology, climatology → Belgium | 
| IRM | Idéale Résidence Mobile | In French | → Construction | 
| IRMB | Institut Royal Météorologique de Belgique | In French | → Meteorology, climatology → Belgium | 
| IRMBP | Institut Royal Météorologique de Belgique, Publications | In French | → Serial publications, periodicals → Meteorology, climatology → Belgium | 
| IRME | Initiator Resistance Measuring Equipment | In English | |
| IRMI | Integrita Retbazita Medio de Informlaborantoj | In Esperanto | → Labour, labour economics | 
| IRN | Interface Revision Notice | In English | → Human-computer interaction | 
| IRN | Interim Revision Notice | In English | |
| IRNIK | Institut für das Recht der Netzwirtschaften, Informations- und Kommunikationstechnologie (www.irnik.de) | In German | → Research institutes → Law, jurisprudence → Computer science → Telecommunications | 
| IRNP | International Review of Nuclear Physics | In English | → Serial publications, periodicals → Nuclear, atomic, and molecular physics | 
| IRO | International Refugee Organization = OIR | Organisation Internationale pour les Réfugiés | In French | In English | → United Nations → Migrations | 
| IRP | Intramural Research Program | In English | |
| IRP | Inertial Reference Package | In English | |
| IRP | Institutions Représentatives du Personnel | In French | → Labour, labour economics | 
| IRPC | International Reviews in Physical Chemistry | In English | → Serial publications, periodicals → Physical chemistry | 
| IRPC | Incubateur Régional de Poitou-Charentes | In French | → Research policy → Engineering, technology → France | 
| IRPI | Institut de Recherche en Propriété Intellectuelle (www.irpi.ccip.fr) | In French | → Research institutes → Artistic property → France | 
| IRPP | Impôt sur le Revenu des Personnes Physiques | In French | → Taxes, duties | 
| IRQ | Institut de Recherche sur le Québec (www.irq.qc.ca) | In French | → Research institutes → Area studies → Canada | 
| IRQ | Interrupt Request | In English | → Computer hardware | 
| IRQ | Idle Repeat Request | In English | → Networks, communication | 
| IRR | Independent Readiness Review | In English | |
| IRR | Initial Requirements Review | In English | |
| IRR | Inspection Rejection Report | In English | |
| IRR | Integral Rocket Ramjet | In English | → Astronautics | 
| IRR | Integrated Readiness Review | In English | |
| IRR | Interface Requirements Review | In English | → Human-computer interaction | 
| IRR | Individual Ready Reserve | In English | → Military affairs | 
| IRRI | International Rice Research Institute (www.irri.org) | In English | → Research institutes → Agricultural sciences | 
| IRRI | International Rice Reserch Institute | In English | → Agricultural sciences | 
| IRRMA | Institut Romand de Recherche Numérique en Physique de Matériaux | In French | → Computer simulation → Physics | 
| IRS | Internal Revenue Service | In English | → Public administration, government | 
| IRS | Institute of Regional Studies | In English | → Area studies | 
| IRS | Interface Requirements Specification | In English | → Human-computer interaction | 
| IRSC | Instituts de recherche en santé du Canada (www.cihr.ca) = CIHR | Canadian Institutes of Health Research | In English | In French | → Research institutes → Biological sciences → Medicine → Canada | 
| IRSEA | Institut de Recherche sur le Sud-Est Asiatique (www.univ-provence.fr/irsea/) | In English | → Research institutes → Area studies | 
| IRSEEM | Institut de Recherche en Systèmes Électroniques Embarqués | In French | → Research institutes → Electronics | 
| IRSN | Institut de Radioprotection et de Sécurité Nucléaire | In French | → Research institutes → Nuclear technology | 
| IRSST | Institut de recherche Robert-Sauvé en santé et sécurité du travail (https://www.irsst.qc.ca) | In French | → Research institutes → Medicine → Accidents, risks, safety → Canada | 
| IRST | Infrared Search Track | In English | |
| IRT | Insuffisance Rénale Terminale | In French | → Physiology → Pathology | 
| IRT | Institut für Rundfunktechnik (www.irt.de) | In German | → Research institutes → Telecommunications → Germany | 
| IRT | In Reference To | In English | |
| IRT | In Regard To | In English | |
| IRTC | International Rehabilitation Council for Torture | In English | → Organizations and associations → Fundamental rights | 
| IRTCM | Integrated Real-Time Contamination Monitor | In English | |
| IRU | Inertial Reference Unit | In English | |
| IRU | IVA Replaceable Unit | In English | |
| IRWA | Iowa Rural Water Association (www.iarwa.org) | In English | → Associations → Environmental technology, water supply, waste management | 
| IS | Internacia Seminario | In Esperanto | → Congresses | 
| IS | International Standard | In English | → Standardization | 
| IS | Installation Support | In English | → Engineering, technology | 
| IS | Instrumentation System | In English | → Engineering, technology | 
| IS | Integrated Satellite | In English | → Astronautics | 
| IS | Interconnecting Station | In English | |
| IS | Image Stabilizer | In English | |
| IS | Informační systém = ИС | Информационная система | In Russian = SI | Sistema d'Informació | In Catalan = IS | Information System | In English = SI | Système d'Information | In French = SI | Sistem Informasi | In Indonesian = IS | Informačný systém | In Slovak = IS | Informacijski sistem | In Slovenian | In Czech | → Software | 
| IS | Information System = ИС, SI (look above) | In English | → Software | 
| IS | Informačný systém = ИС, SI (look above) | In Slovak | → Software | 
| IS | Informacijski sistem = ИС, SI (look above) | In Slovenian | → Software | 
| IS | Intervention de Sécurité | In French | → Accidents, risks, safety | 
| IS | International Sign | In English | → Linguistics | 
| IS-IS | Intermediate-System to Intermediate-System | In English | → Networks, communication | 
| ISA | International Sociological Association | In English | → Associations → Sociology | 
| ISA | Institut Supérieur de l'Administration | In French | → Specialized or polytechnical colleges | 
| ISA | Inertial Sensor Assembly | In English | |
| ISA | Instruction Set Architecture | In English | |
| ISA | Instructional Systems Approach | In English | |
| ISA | Interim Stowage Assembly | In English | |
| ISA | Information Spatiale et Archéologie | In French | → Geodesy, cartography → Archeology | 
| ISA | Institut Supérieur d'Agriculture | In French | → Agricultural sciences | 
| ISA | Invest in Sweden Agency | In English | → 33972 | 
| ISA | International Seabed Authority (www.isa.org.jm) | In English | → Organizations and associations → International relations → Marine research, oceanography → Mining |