| RCSO-TIC | Réseau de Compétences de Suisse Occidentale en Technologie de l'Information et de la Communication | In French | → Telecommunications |
| RDA | Remote Data Access | In English | → Data → Networks, communication |
| RDA | Resident Data Area | In English | → Data |
| RDA | Rich Desktop Application | In English | → Software |
| RDBMS | Relational Database Management System |
In English | → Data → Knowledge management |
| RDDL | Resource Directory Description Language | In English | → Programming languages → Data |
| RDF | Ressource Description Format | In English | → Data |
| RDF | Resource Data File | In English | → Data |
| RDF | Resource Description Framework | In English | → Data → Networks, communication |
| RDGS | Reconfiguration Display Generation System | In English | → Human-computer interaction |
| RDM | Real-Time Data Manager | In English | → Software → Data |
| RDO | Relational Database Operator | In English | → Data |
| RDOS | Real-Time Disk Operating System | In English | → Operating systems |
| RDR | Raw Data Recorder | In English | → Data |
| REACCIUN | Red Académica de Centros de Investigación y Universidades Nacionales | In Spanish | → Education → Telecommunications |
| RECON | Remote Console | In English | → Human-computer interaction |
| RedCYT | Red Científica y Tecnológica | In Spanish | → Mathematics and natural sciences → Applied sciences, technology → Telecommunications |
| RENATA | Red Nacional Académica de Tecnología Avanzada | In Spanish | → Telecommunications |
| RENATER | Réseau National de Télécommunication pour la Technologie, l'Enseignement et la Recherche | In French | → Research policy → Networks, communication → Education → Engineering, technology |
| RENIA | Red Nicaragüense de Internet Avanzada | In Spanish | → Telecommunications |
| REST | Representational State Transfer | In English | |
| RET | Resolution Enhancement Technology | In English | → Peripheral devices → Graphic industries, printing, publishing |
| RETINA | Red TeleInformática Académica | In Spanish | → Telecommunications |
| REUNA | Red Universitaria Nacional | In Spanish | → Higher education, universities → Telecommunications |
| REVES | Rendu et Environnements VirtuEls Sonorisés | In French | → Computer-based techniques |
| REX | Remote Events for XML | In English | → Software → Networks, communication |
| RFCP | Request For Computer Program | In English | → Software |
| RFDU | Radio Frequency and Digital Unit | In English | → Telecommunications |
| RFHA | Reusable Flight Hardware Authorization | In English | → Hardware → Aeronautics, aircraft → Spaceflight engineering, astronautics |
| RFI | Remote File Inquiry | In English | → Software |
| RFIA | Reconnaissance des Formes et Intelligence Artificielle | In French | → Congresses → Artificial intelligence → Computer-based techniques |
| RFID | Radio Frequency Identification | In English | → Telecommunications |
| RGC | Réalisation interne à Géométrie Contrainte | In French | → Computer-based techniques |
| RGC | Retro-Gaming Connexion | In English | → Software → Entertainment |
| RGD | Régie de Gestion des Données | In French | → Public administration, government → Knowledge management |
| RHEC | Radiation-Hardened Emulating Computer | In English | → Hardware |
| RIA | Rich Internet Application | In English | → Software → Networks, communication |
| RIA | Rich Internet Applications | In English | → Software → Networks, communication |
| RIAM | Recherche et Innovations en Audiovisuel et Multimédia | In French | → Computer-based techniques → Cinema, movies |
| RIAP | Rural Internet Access Point | In English | → Networks, communication |
| RIC | Reta Informado-Centro | In Esperanto | → Libraries → Networks, communication |
| RICAM | Johann Radon-Institut für computerorientierte und angewandte Mathematik | In German | → Research institutes → Mathematics |
| RICC | Remote Intercomputer Communications | In English | → Networks, communication → Telecommunications |
| RICP | Real-Time Interactive Computer Program | In English | → Software |
| RIDS | Rockwell Integrated Defense Simulator | In English | → 355 → Computer simulation |
| RIE | Righi Interface Engineering | In English | → Human-computer interaction |
| RIP | Routing Information Protocol | In English | → Networks, communication |
| RIP | Raster Image Processor | In English | → Graphical processing → Image processing |
| RIS | Revue, Informatique et Statistique dans les sciences humaines | In French | → Serial publications, periodicals → Computer-based techniques → Social sciences → Statistics |
| RIS | Rauminformationssystem | In German | → Software → Geography |
| RIS | Rechtsinformationssystem | In German | → Data → Law, jurisprudence |
| RISC | Reduced Instruction Set Computer | In English | → Hardware |
| RIT | Request for Interface Tooling | In English | → Human-computer interaction |
| RIU | Remote Interface Unit | In English | → Human-computer interaction |
| RMI | Remote Method Invocation | In English | → Networks, communication |
| RMS | Random Motion Simulator | In English | → Computer simulation |
| RNIL | Réseau National d'Ingénierie Linguistique | In French | → Computer-based techniques → Linguistics |
| RNP | Rede Nacional de Ensino e Pesquisa | In Portuguese | → Telecommunications |
| RNRE | Réseau National de Recherche et d'Éducation | In French | → Research policy → Networks, communication → Education |
| RNTL | Réseau National de Recherche et d'Innovation en Technologies Logicielles | In French | → Software |
| RNTL | Réseau National des Technologies Logicielles | In French | → Organizations and associations → Software |
| ROC | Reconnaissance Optique de Caractères = ORC | Optical Character Recognition | In English |
In French | → Writing systems → Computer-based techniques |
| ROLAP | Relational On Line Analytical Processing | In English | → Knowledge management → Data |
| ROM | Read Only Memory | In English | → Memories |
| ROS | Read-Only Storage | In English | → Memories |
| ROSES | Rockwell Operational Software Engineering System | In English | → Software |
| RSCS | Remote Spooling and Communication Subsystem | In English | → Software → Networks, communication |
| RSDP | Remote Site Data Processor | In English | → Data |
| RSN | Robust Security Network | In English | → Networks, communication → Telecommunications |
| RSS | RDF Site Summary | In English | → Networks, communication |
| RSS | Really Simple Syndication | In English | → Networks, communication |
| RSSI | Responsable de la Sécurité des Systèmes d'Information = CISO | Chief Information Security Officer | In English |
In French | |
| RST | Recessed Selectomatic Terminal | In English | → Human-computer interaction |
| RSTP | Rapid Spanning Tree Protocol | In English | → Networks, communication → Telecommunications |
| RSU | Remote Service Unit | In English | → Networks, communication |
| RTC | Real-Time Computer | In English | → Hardware |
| RTC | Real-Time Clock | In English | |
| RTCC | Real-Time Computer Complex | In English | → Hardware |
| RTCC | Real-Time Computer Command | In English | → Hardware |
| RTCC | Real-Time Computer Center | In English | → Hardware |
| RTCP | Real-Time Communications Processor | In English | → Hardware → Telecommunications |
| RTCPS | Real-Time Computer Program System | In English | → Software |
| RTCS | Real-Time Computer System | In English | → Hardware → Software |
| RTD | Real-Time Display | In English | → Human-computer interaction |
| RTD | Real-Time Data | In English | → Data |
| RTF | Rich Text Format | In English | → Document processing |
| RTFSS | Real-Time Flight Safety Software | In English | → Software → Aeronautics, aircraft → Spaceflight engineering, astronautics |
| RTIF | Real-Time Interface | In English | → Human-computer interaction |
| RTM | Réseaux, Télécoms et Multimedia | In French | → Networks, communication → Document processing → Telecommunications |
| RTOLAP | Real-Time On Line Analytical Processing | In English | → Knowledge management → Data |
| RTS | Real-Time Strategy = STR | Stratégie en Temps Réél | In French |
In English | → Entertainment |
| RTSF | Real-Time Simulation Facility | In English | → Computer simulation |
| RTSS | Real-Time Simulation System | In English | → Computer simulation |
| RTT | Round Trip Time | In English | → Networks, communication |
| RTU | Remote Terminal Unit | In English | → Human-computer interaction |
| RUSHES | Retrieval of mUltimedia Semantic units for enHanced rEuSability | In English | → Computer-based techniques |
| RVA | Réseaux à Valeur Ajoutée | In French | → Networks, communication |
| RVN | Réseau des Villes Numériques | In French | |
| RWM | Read and Write Memory | In English | → Memories |
| S2S^2 | Sound to Sense, Sense to Sound | In English | → Computer-based techniques |
| S3IT | Schéma Stratégique des Systèmes d'Information et des Télécommunications | In French | → Telecommunications |
| SaaS | Software as a Service | In English | → Software → Networks, communication |
| SACS | Software Avionics Command Support | In English | → Software → Aeronautics, aircraft |
| SAFARI | Shape Analysis For Automatic Retrieval of Images | In English | → Image processing |
| SAG | SQL Access Group | In English | → Data |
| SALERO | Semantic Audiovisual Entertainment Reusable Objects (www.salero.info) | In English | → Computer-based techniques → Telecommunications → Entertainment |
| SALUG | Savoie-Aravis Linux Users Group | In English | → Organizations and associations → Operating systems |
| SAML | Security Assertion Markup Language | In English | → Programming languages |
| SAMS | Systems Analysis Modelling Simulation | In English | → Serial publications, periodicals → Computer simulation |
| SAMT | Semantics And digital Media Technologies | In English | → Computer-based techniques → Telecommunications |
| SAN | Storage Area Network | In English | → Data → Knowledge management |
| SANDAC | Sandia Airborne Computer Guidance System | In English | → Hardware → Aeronautics, aircraft |
| SAPIR | Search on Audio-visual content using Peer-to-peer Information Retrieval | In English | → Computer-based techniques → Knowledge management |
| SAR | Storage Address Register | In English | → Memories |
| SARAI | South Asia Resource Access on the Internet | In English | → Libraries → Networks, communication → Area studies |
| SAS | Software Approval Sheet | In English | → Software |
| SAS | Software Automation Subpanel | In English | → Software |
| SASCB | Shuttle Avionics Software Control Board | In English | → Software → Aeronautics, aircraft → Spaceflight engineering, astronautics |
| SASL | Simple Authentication and Security Layer | In English | → Networks, communication |
| SASTP | Stand-Alone Self-Test Program | In English | → Software |
| SAVANT | Synchronised and scalable Audio Video content Across NeTworks | In English | → Networks, communication → Computer-based techniques → Telecommunications → Music |
| SB | Synchronization Bit | In English | |
| SBE | Sub-Bit Encoder | In English | |
| SBML | Systems Biology Markup Language | In English | → Programming languages → Biological sciences |
| SBO | Systems Biology Ontology | In English | → Programming languages → Knowledge management → Libraries → Biological sciences |
| SC | Software Change | In English | → Software |
| SCA | Software Command Analysis | In English | → Software |
| SCAM | Société Civile des Auteurs Multimédia (www.scam.fr) | In French | → Organizations and associations → Cinema, movies |
| SCATS | Sydney Co-ordinated Adaptive Traffic System | In English | → Software → Transport and postal services |
| SCB | Software Control Board | In English | → Software |
| SCC | Simulation Configuration Control | In English | → Computer simulation |
| SCC | Scientific Computing Center | In English | |
| SCCB | Software Configuration Control Board | In English | → Software |
| SCCB | Software Change Control Board | In English | → Software |
| SCCH | Software Competence Center Hagenberg (www.scch.at) | In English | → Software |
| SCDR | Software Critical Design Review | In English | → Software |
| SCI | Software Customer Inspection | In English | → Software |
| SCM | System Configuration Monitoring | In English | → Hardware |
| SCM | System Control Module | In English | → Hardware |
| SCM | Software Configuration Management/Manager | In English | → Software |
| SCM | System Configuration Management | In English | → Hardware |
| SCMO | Software Configuration Management Office | In English | → Software |
| SCMP | Software Configuration Management Plan | In English | → Software |
| SCMU | Satellite Control and Monitor Unit | In English | → Human-computer interaction → Spaceflight engineering, astronautics |
| SCOS | Subsystem Computer Operating System | In English | → Operating systems |
| SCR | Software Change Request | In English | → Software |
| SCRB | Software Configuration Review Board | In English | → Software |
| SCS | Solutions Communicantes Sécurisées | In French | → Software → Networks, communication → Telecommunications |
| SCSI | Small Computer System Interface | In English | → Human-computer interaction |
| SCSL | Scientific Computing Software Library | In English | → Software |
| SCSS | Satellite Control Simulation System | In English | → Computer simulation → Spaceflight engineering, astronautics |
| SCTP | Stream Control Transmission Protocol | In English | → Internet |
| SCTS | Secondary Clear To Send | In English | → Data → Telecommunications |
| SCW | Search-Complete Word | In English | → Document processing |
| SDA | Source Data Automation | In English | → Data |
| SDBC | Software Development Baseline Control | In English | → Software |
| SDC | Software Development Computer | In English | → Hardware → Software |
| SDCD | Secondary Carrier Detect | In English | → Data → Telecommunications |
| SDD | Software Description Document | In English | → Software |
| SDD | System for Distributed Data base | In English | → Data |
| SDD | Software Design Document | In English | → Software |
| SDDD | Software Detailed Design Document | In English | → Software |
| SDDL | Software Design and Document Language | In English | → Software |
| SDDS | Special Data Dissemination Standards | In English | → Standardization → Data |
| SDE | Software Development Environment | In English | → Software |
| SDF | Software Development Facility | In English | → Software |
| SDF | Simulation Data File | In English | → Computer simulation |
| SDF | Software Development File | In English | → Software |
| SDH | Software Development Handbook | In English | → Software |
| SDHS | Satellite Data Handling System | In English | → Data → Spaceflight engineering, astronautics |
| SDIF | Software Development and Integration Facility | In English | → Software |
| SDIL | Spacecraft DCD Interface Logic | In English | → Human-computer interaction → Spaceflight engineering, astronautics |
| SDK | Software Development Kit | In English | → Software |
| SDL | Simple Directmedia Layer | In English | → Software |
| SDL | Software Development Library | In English | → Software |
| SDL | Software Development Laboratory | In English | → Research institutes → Software |
| SDM | Shuttle Data Management | In English | → Data → Spaceflight engineering, astronautics |
| SDN | Software Development Note | In English | → Software |
| SDNS | Secure Data Network System | In English | → Data → Networks, communication |
| SDP | Sensor Data Processing | In English | |
| SDP | Site Data Processor | In English | → Data |
| SDP | Standard Data Processor | In English | → Hardware |
| SDP | Software Development Plan | In English | → Software |
| SDP | Shuttle Data Processor | In English | → Data → Spaceflight engineering, astronautics |
| SDPC | Shuttle Data Processing Complex | In English | → Data → Spaceflight engineering, astronautics |
| SDR | Software Design Review | In English | → Software |
| SDR | Sensor Data Record | In English | → Data |
| SDR | Serial Data Receiver | In English | → Data |
| SDR | Software Design Requirement | In English | → Software |
| SDR | Storage Data Register | In English | → Data |
| SDRAM | Synchronous Dynamic Random Access Memory | In English | → Memories |
| SDRB | Software Design Review Board | In English | → Software |
| SDRS | Shuttle Display Reconfiguration System | In English | → Human-computer interaction → Spaceflight engineering, astronautics |
| SDS | Satellite Data System | In English | → Data → Spaceflight engineering, astronautics |
| SDS | Scientific Data System | In English | → Data |
| SDS | Simulation Data Subsystem | In English | → Computer simulation |
| SDS | Software Design Specification | In English | → Software |
| SDSC | San Diego Supercomputing Center | In English | |
| SDT | Shuttle Data Tape | In English | → Data → Spaceflight engineering, astronautics |
| SDVF | Software Development and Verification Facility | In English | → Software |